Biological Reactors (Option)


Environmental and Biological Engineering, Publication in the Diário da República - NI n.º1417|EAB|ESTT|2011

5.5 ECTS; 3º Ano, 2º Semestre,


Basic knowledge of microbiology, biochemistry, reactors and mass and heat transfer calculations.

The students should gain skills to make research and collect laboratory data about the global kinetics of microbial processes so as to be able to select the right digester and mode of operation as well as design the vessel and the respective mixing aeration and cooling devices.

Stoichiometry and kinetics of microbial growth. Design and
analysis of biological reactors: batch reactor, continuous-flow
stirred-tank, fed-batch, CSTR with recycle and wall growth, plugflow
reactor with recycle, bubble-column, fluidized-bed, trickle-bed,
CSTRs in series, association CSTR-PFR. Oxygen-limited fermentations. Heat balance, sterilisation. Scale-up criteria. Case studies.

Evaluation Methodology
Final written test and reports on laboratory coursework. Minimum pass mark: 9/20 in each assessment component.

- Fonseca, M. e Teixeira, J. (2007). Reactores Biológicos - Fundamentos e Aplicações. Lisboa: LIDEL edições técnicas
- Doran, P. (2012). Bioprocess Engineering Principles. London: Academic Press
- Kristiansen, B. e Ratledge, C. (2006). Basic Biotechnology. London: Cambridge University Press
- Mateus, D. (0). Sebentas de Reactores Biológicos. Acedido em 1 de fevereiro de 2012 em

Method of interaction
Lectures and laboratory sessions including experimental work.

Software used in class